Some data on the performance of PG 7.1 with the default 8KB blocksize vs. a larger blocksize would be interesting to have, Pascal. I've not played with this at all. I would think a larger blocksize would be better on larger systems and a smaller blocksize on smaller systems but that is nothing but intuition speaking.
You can emulate a smaller system on a larger box by varying the "-B" parameter given the postmaster along with changing the blocksize and recompiling PG.