Galileo found slow (cpu eaters) on /admin/users pages, plus in /dotlrn/admin pages, we'll post specifics plus patches as well.
Also the login is a bit slow.
In the PG case, some troubles with the CR and inline query function calls that does sequential scans.
Now moving all the lob's to the file system (file-storage & now evaluation supports storage on the file system as well!), lob calls tend to be slow in PG.
Specifics comming ...