Ola,
I had the same problem yesterday. It seems to be host-node map related. Tail the log, and you should see the query it stops on when you request a page. No error shows up in the log that I could find. I was just getting connection refused. I noticed that my system was saying connection refused by dave.deepskydesign.com even though I was using the IP address in the location bar. So perhaps adding an entry to the host-node map will help.
The search indexer runs every 30 seconds so I can often scroll by in the log while you are looking for a real error message.
I dropped my database and recreated it, and reloaded OpenACS and it was working again. Sorry, I didn't troubleshoot it further, I thought it was something I had done to my system.
If you don't need any of the data, this is an ok solution.