I think the problem with applying p2p to most openACS sites is that the communities aren't really distributed. Since you can host multiple separate-but-related communities on the same instance (ie greenpeace), and easily search across them, how likely is it that the overhead of JUXTA will pay off?
There *are* some db items that cut across sites that I'd love to see a p2p search approach for: job boards/classified ads/academic journals. But, I don't think the concept applies to OpenACS sites in general.