Maybe the latest OpenACS would work ok with Tcllib 1.21, I don't know.
The problem is the interaction between Tcl and tcllib. It also occurs without OpenACS. The problem is fixed in the repository. So, when using the newest version of Tcl 8.6 from fossil, or when the next release of Tcl 8.6 or newer happens, tcllib 1.21 will work. If one relies on released versions/binaries, stick with tcllib 1.20.
Some words to Tcl9: The new flagship version of Tcl will be released soon (I know, since is said since at least a year, but now it looks realistic). This version brings true 64bit sizes for Tcl_Objs (the 2GB limit is gone) has many changes both on the C and the Tcl layer. While the C infrastructure (NaviServer/XOTcl/tDOM/ - newest and partly not-released versions) is ported and running with Tcl9, OpenACS will require some changes (checkout the long list of changes that were necessary for tcllib [2], I expect similar changes will be needed for OpenACS).
The plan is to get first OpenACS 5.10.1 out, and not to delay the process. For the Tcl9 compatible versions, we should create a new branch to avoid instabilities in the oacs-5-10 branch.
[1] https://wiki.tcl-lang.org/page/Porting+extensions+to+Tcl+9
[2] https://openacs.org/conf2023/info/download/file/porting-tcllib-tcl9.pdf